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The Spokane region’s largest private employer is Sacred Heart Medical Center & Children’s Hospital. Other top employers span across most industry sectors with health care leading the way followed by energy, manufacturing, education and others.
| Company Name | Full Time Emp. | Business Activity |
| Sacred Heart Medical Center and Children's Hospital |
3,485 |
Health Care |
| Northern Quest, A Kalispel Casino |
1,356 |
Casino, restaurant, entertainment |
| URM Stores Inc. |
1,353 |
Wholesale Distribution and Retail Grocery |
| Gonzaga University |
1,111 |
Education |
| Avista Corp. |
950 |
Energy Company |
| Holy Family Hospital |
908 |
Health Care |
| The BNSF Railway Co. |
900 |
Railroad |
| Inland Northwest Health Services |
868 |
Health care. Operates St. Luke's Rehabilitation Institute, Community Health Education & Resources, Northwest TeleHealth, and other entities |
| Rockwood Clinic PS |
850 |
Health Care |
| Kaiser Aluminum & Chemical Corp. |
800 |
Aluminum Rolling Mill |
| CPM Devolpment Corp. |
750 |
Sand & gravel, ready-mix concrete, asphalt paving |
| Sterling Savings Bank |
669 |
Banking |
| Lakeland Village |
580 |
Residential Habilitation Services |
| Bank of America |
540 |
Banking and Financial Services |
| Yoke's Foods Inc. |
508 |
Retail Grogery |
| Itron Inc. |
474 |
Automated meter data collection and management |
| Trans-Systems Inc. |
449 |
Transportation/Trucking |
| The Spokesman-Review |
383 |
Media and Newspaper |
| Huntwood Industries |
327 |
Custom kitchen cabinets and office furniture |
Source: Journal of Business - Book of Lists 2010
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